The fifth-year residents return for the first day of a year that will make or break their careers Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital; April tries to step up to the plate as Chief Resident in the wake of a giant sinkhole in the middle of Seattle; and Cristina and Owen are still at odds over their drastically different feelings for their unborn child.
The series follows smart, capable and by the book Grace Narayan (Anjli Mohindra), who was flying high as an inner-city police sergeant before being forced into a 'punishment posting' on the small, antiquated island of St. Jory. Confronted by the forgotten and unsolved case of missing teenage boy Cai, Grace quickly discovers that she must overcome scarce evidence, extraordinary local characters, and the island's strange cult history to uncover the truth.